A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa

Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Afr...

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Autores principales: Andersen, Lena S, Magidson, Jessica F, O’Cleirigh, Conall, Remmert, Jessica E, Kagee, Ashraf, Leaver, Matthew, Stein, Dan J, Safren, Steven A, Joska, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081274/
https://www.ncbi.nlm.nih.gov/pubmed/27121977
http://dx.doi.org/10.1177/1359105316643375
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author Andersen, Lena S
Magidson, Jessica F
O’Cleirigh, Conall
Remmert, Jessica E
Kagee, Ashraf
Leaver, Matthew
Stein, Dan J
Safren, Steven A
Joska, John
author_facet Andersen, Lena S
Magidson, Jessica F
O’Cleirigh, Conall
Remmert, Jessica E
Kagee, Ashraf
Leaver, Matthew
Stein, Dan J
Safren, Steven A
Joska, John
author_sort Andersen, Lena S
collection PubMed
description Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa (n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvements in mood through a 3-month follow up. Antiretroviral therapy adherence was maintained during the intervention period. Participant retention supports acceptability; however, modest provider fidelity despite intensive supervision warrants additional attention to feasibility. Future effectiveness research is needed to evaluate this nurse-delivered cognitive behavioral therapy intervention for adherence and depression in this context.
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spelling pubmed-50812742018-05-01 A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa Andersen, Lena S Magidson, Jessica F O’Cleirigh, Conall Remmert, Jessica E Kagee, Ashraf Leaver, Matthew Stein, Dan J Safren, Steven A Joska, John J Health Psychol Articles Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa (n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvements in mood through a 3-month follow up. Antiretroviral therapy adherence was maintained during the intervention period. Participant retention supports acceptability; however, modest provider fidelity despite intensive supervision warrants additional attention to feasibility. Future effectiveness research is needed to evaluate this nurse-delivered cognitive behavioral therapy intervention for adherence and depression in this context. SAGE Publications 2016-04-26 2018-05 /pmc/articles/PMC5081274/ /pubmed/27121977 http://dx.doi.org/10.1177/1359105316643375 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Articles
Andersen, Lena S
Magidson, Jessica F
O’Cleirigh, Conall
Remmert, Jessica E
Kagee, Ashraf
Leaver, Matthew
Stein, Dan J
Safren, Steven A
Joska, John
A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title_full A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title_fullStr A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title_full_unstemmed A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title_short A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
title_sort pilot study of a nurse-delivered cognitive behavioral therapy intervention (ziphamandla) for adherence and depression in hiv in south africa
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081274/
https://www.ncbi.nlm.nih.gov/pubmed/27121977
http://dx.doi.org/10.1177/1359105316643375
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