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Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells

Mutational status of TP53 together with expression of wild-type (wt) IGHV represents the most widely accepted biomarkers, establishing a very poor prognosis in B-cell chronic lymphocytic leukemia (B-CLL) patients. Adoptive cell therapy using allogeneic HLA-mismatched Natural killer (NK) cells has em...

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Detalles Bibliográficos
Autores principales:	Sánchez-Martínez, Diego, Lanuza, Pilar M., Gómez, Natalia, Muntasell, Aura, Cisneros, Elisa, Moraru, Manuela, Azaceta, Gemma, Anel, Alberto, Martínez-Lostao, Luis, Villalba, Martin, Palomera, Luis, Vilches, Carlos, García Marco, José A., Pardo, Julián
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081347/ https://www.ncbi.nlm.nih.gov/pubmed/27833611 http://dx.doi.org/10.3389/fimmu.2016.00454

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