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Replication-Independent Histone Variant H3.3 Controls Animal Lifespan through the Regulation of Pro-longevity Transcriptional Programs

Chromatin structure orchestrates the accessibility to the genetic material. Replication-independent histone variants control transcriptional plasticity in postmitotic cells. The life-long accumulation of these histones has been described, yet the implications on organismal aging remain elusive. Here...

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Detalles Bibliográficos
Autores principales:	Piazzesi, Antonia, Papić, Dražen, Bertan, Fabio, Salomoni, Paolo, Nicotera, Pierluigi, Bano, Daniele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081402/ https://www.ncbi.nlm.nih.gov/pubmed/27760329 http://dx.doi.org/10.1016/j.celrep.2016.09.074

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