Cargando…
Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue
Previous work indicated that lysine-specific demethylase 1 (Lsd1) can positively regulate the oxidative and thermogenic capacities of white and beige adipocytes. Here we investigate the role of Lsd1 in brown adipose tissue (BAT) and find that BAT-selective Lsd1 ablation induces a shift from oxidativ...
Autores principales: | Duteil, Delphine, Tosic, Milica, Lausecker, Franziska, Nenseth, Hatice Z., Müller, Judith M., Urban, Sylvia, Willmann, Dominica, Petroll, Kerstin, Messaddeq, Nadia, Arrigoni, Laura, Manke, Thomas, Kornfeld, Jan-Wilhelm, Brüning, Jens C., Zagoriy, Vyacheslav, Meret, Michael, Dengjel, Jörn, Kanouni, Toufike, Schüle, Roland |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081406/ https://www.ncbi.nlm.nih.gov/pubmed/27760309 http://dx.doi.org/10.1016/j.celrep.2016.09.053 |
Ejemplares similares
-
Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4
por: Castex, Josefina, et al.
Publicado: (2017) -
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells
por: Tosic, Milica, et al.
Publicado: (2018) -
The histone code reader Spin1 controls skeletal muscle development
por: Greschik, Holger, et al.
Publicado: (2017) -
LSD1 promotes oxidative metabolism of white adipose tissue
por: Duteil, Delphine, et al.
Publicado: (2014) -
Nitroreductase‐Mediated Release of Inhibitors of Lysine‐Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells
por: Herrlinger, Eva‐Maria, et al.
Publicado: (2020)