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Critical role for adenosine receptor A2a in β-cell proliferation
OBJECTIVE: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating β-cell proliferation is unknown. The objective of t...
Autores principales: | Schulz, Nadja, Liu, Ka-Cheuk, Charbord, Jérémie, Mattsson, Charlotte L., Tao, Lingjie, Tworus, Dominika, Andersson, Olov |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081418/ https://www.ncbi.nlm.nih.gov/pubmed/27818940 http://dx.doi.org/10.1016/j.molmet.2016.09.006 |
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