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First Report of AIDS-Related Burkitt's Lymphoma Presenting as Bilateral Orbital Masses

Burkitt's lymphoma (BL) is an aggressive B-cell non-Hodgkin's lymphoma and one of the fastest growing tumors in humans. It is an acquired immunodeficiency syndrome- (AIDS-) defining disease and occurs with relatively preserved CD4 cell counts. It rarely affects the orbital region in the se...

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Detalles Bibliográficos
Autores principales: Alves de Almeida, Monica, Nesi Cardoso Migliano Porto, Juliana, de Brito Lyra, Ana Carolina, Calheiros Leite, Luiz Arthur, Basilio-de-Oliveira, Rodrigo Panno, Neves-Motta, Rogério, Correa, Andréa Ramos, Raphael de Almeida Ferry, Fernando, Eyer-Silva, Walter de Araujo, Grechi Pacheco, Ronaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081451/
https://www.ncbi.nlm.nih.gov/pubmed/27818811
http://dx.doi.org/10.1155/2016/6469528
Descripción
Sumario:Burkitt's lymphoma (BL) is an aggressive B-cell non-Hodgkin's lymphoma and one of the fastest growing tumors in humans. It is an acquired immunodeficiency syndrome- (AIDS-) defining disease and occurs with relatively preserved CD4 cell counts. It rarely affects the orbital region in the setting of AIDS. We report unusual presentation of a fatal case of AIDS-associated BL in a 42-year-old female patient with severe CD4 cell depletion who presented with dramatic fast growing (within days) bilateral orbital masses leading to striking facial deformities. To the best of our knowledge, this is the first report of bilateral orbital involvement in AIDS-associated BL.