Cargando…

Diffuse PTH expression in parathyroid tumors argues against important functional tumor subclones

OBJECTIVE: Primary hyperparathyroidism is usually characterized by a monoclonal parathyroid tumor secreting excess parathyroid hormone (PTH). The main regulator of PTH secretion is calcium and the calcium–PTH set point is shifted in parathyroid tumor cells. We sought to investigate the relationship...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haglund, Felix, Juhlin, C Christofer, Kiss, Nimrod B, Larsson, Catharina, Nilsson, Inga-Lena, Höög, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2016
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081673/ https://www.ncbi.nlm.nih.gov/pubmed/26865585 http://dx.doi.org/10.1530/EJE-15-1062

Ejemplares similares

Inflammatory infiltrates in parathyroid tumors
por: Haglund, Felix, et al.
Publicado: (2017)

Genetic characterization of large parathyroid adenomas
por: Sulaiman, Luqman, et al.
Publicado: (2012)

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight
por: Haglund, Felix, et al.
Publicado: (2015)

Solid Cell Nests Within a Parathyroid Gland—Report of an Exceptional Case
por: Juhlin, C. Christofer, et al.
Publicado: (2018)

Lipoadenoma of the Parathyroid Gland: Characterization of an Institutional Series Spanning 28 Years
por: Juhlin, C. Christofer, et al.
Publicado: (2020)

Genome-Wide and Locus Specific Alterations in CDC73/HRPT2-Mutated Parathyroid Tumors
por: Sulaiman, Luqman, et al.
Publicado: (2012)

Parafibromin as a Diagnostic Instrument for Parathyroid Carcinoma-Lone Ranger or Part of the Posse?
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

Acquired hypermethylation of the P16(INK4A) promoter in abdominal paraganglioma: relation to adverse tumor phenotype and predisposing mutation
por: Kiss, Nimrod B, et al.
Publicado: (2013)

Prolactin Receptor in Primary Hyperparathyroidism – Expression, Functionality and Clinical Correlations
por: Haglund, Felix, et al.
Publicado: (2012)

Minimally invasive follicular thyroid carcinomas: prognostic factors
por: Stenson, Gustav, et al.
Publicado: (2016)

The VHL gene is epigenetically inactivated in pheochromocytomas and abdominal paragangliomas
por: Andreasson, Adam, et al.
Publicado: (2013)

High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma
por: Mu, Ninni, et al.
Publicado: (2018)

Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center
por: Hellgren, L. Samuel, et al.
Publicado: (2022)

Clinical Routine Application of the Second-generation Neuroendocrine Markers ISL1, INSM1, and Secretagogin in Neuroendocrine Neoplasia: Staining Outcomes and Potential Clues for Determining Tumor Origin
por: Juhlin, Carl Christofer, et al.
Publicado: (2020)

Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease
por: Hysek, Martin, et al.
Publicado: (2019)

A Case of a Rare Parathyroid Hormone (PTH)-Producing Neuroendocrine Tumor
por: Quinn, Catherine Dianne, et al.
Publicado: (2022)

How to Argue
Publicado: (1855)

How to Argue
Publicado: (1880)

How to Argue
Publicado: (1878)

Genomics and Epigenomics in Parathyroid Neoplasia: from Bench to Surgical Pathology Practice
por: Juhlin, C. Christofer, et al.
Publicado: (2020)

Parathyroid Adenoma With Respiratory-Like Epithelium: Case Report of a Potential Mimic With Unknown Etiology
por: Juhlin, C. Christofer, et al.
Publicado: (2021)

Distinguishing between thyroid and parathyroid nodules by ultrasound: a potential game-changer in clinical practice?
por: Juhlin, C. Christofer, et al.
Publicado: (2023)

Metastatic Neuroendocrine Neoplasms of Unknown Primary: Clues from Pathology Workup
por: Juhlin, Carl Christofer, et al.
Publicado: (2022)

Accurate Identification of Subclones in Tumor Genomes
por: Ahmadinejad, Navid, et al.
Publicado: (2022)

Intraoperative parathyroid hormone (PTH) testing in patients with primary hyperparathyroidism and PTH levels in the normal range
por: Medas, Fabio, et al.
Publicado: (2019)

Arguing from Ignorance
por: Cummings, Louise
Publicado: (2020)

Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors
por: Fotouhi, Omid, et al.
Publicado: (2016)

Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions
por: Dinets, Andrii, et al.
Publicado: (2015)

Exploring the Eco-Evolutionary Dynamics of Tumor Subclones
por: Rampias, Theodoros
Publicado: (2020)

Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
por: Kumar, Satendra, et al.
Publicado: (2019)

OR07-01 Identification of the First Case of Acquired Autoimmune Parathyroid Hormone (PTH) Resistance Due to PTH1 Receptor (PTH1R) Autoantibodies
por: Mandl, Adel, et al.
Publicado: (2020)

Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
por: Hellgren, L Samuel, et al.
Publicado: (2022)

Neonatal transient pseudohypoparathyroidism: could it be included among inactivating parathyroid hormone (PTH)/PTH-related protein signalling disorders?
por: De Rose, Domenico Umberto, et al.
Publicado: (2019)

Metastatic malignant melanoma with neuroendocrine differentiation: a case report and review of the literature
por: Juhlin, Carl Christofer, et al.
Publicado: (2020)

Rare PTH Gene Mutations Causing Parathyroid Disorders: A Review
por: Lee, Joon-Hyop, et al.
Publicado: (2020)

Malignant Hypercalcemia Induced by the Ectopic Production of Intact Parathyroid Hormone (PTH)
por: Neves, Ana, et al.
Publicado: (2023)

Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
por: Åhlén, Jan, et al.
Publicado: (2018)

Reversed whole PTH/intact PTH ratio as an indicator of marked parathyroid enlargement: five case studies and a literature review
por: Komaba, Hirotaka, et al.
Publicado: (2008)

How to argue: powerfully, persuasively, positively
por: Herring, Jonathan
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_is9ttv561tmg4tg4e1hl734rdj