Cargando…

Granular Cell Tumour of the Larynx

A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, po...

Descripción completa

Detalles Bibliográficos
Autores principales: Sproat, Rhona, Wong, Gentle, Rubin, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082060/
https://www.ncbi.nlm.nih.gov/pubmed/27325237
http://dx.doi.org/10.1007/s12105-016-0736-3
_version_ 1782463002138640384
author Sproat, Rhona
Wong, Gentle
Rubin, John
author_facet Sproat, Rhona
Wong, Gentle
Rubin, John
author_sort Sproat, Rhona
collection PubMed
description A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, positive for S-100 staining. This confirmed a granular cell tumour. CO(2) laser was utilised to excise this benign tumour. Granular cell tumours of the head and neck are common, but are infrequently found in the larynx. This case report highlights the importance for the otolaryngologist to be aware of this differential diagnosis, particularly as histologically they may be confused with squamous cell carcinoma.
format Online
Article
Text
id pubmed-5082060
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-50820602016-11-09 Granular Cell Tumour of the Larynx Sproat, Rhona Wong, Gentle Rubin, John Head Neck Pathol Sine qua non Clinicopathologic Correlation A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, positive for S-100 staining. This confirmed a granular cell tumour. CO(2) laser was utilised to excise this benign tumour. Granular cell tumours of the head and neck are common, but are infrequently found in the larynx. This case report highlights the importance for the otolaryngologist to be aware of this differential diagnosis, particularly as histologically they may be confused with squamous cell carcinoma. Springer US 2016-06-20 /pmc/articles/PMC5082060/ /pubmed/27325237 http://dx.doi.org/10.1007/s12105-016-0736-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Sine qua non Clinicopathologic Correlation
Sproat, Rhona
Wong, Gentle
Rubin, John
Granular Cell Tumour of the Larynx
title Granular Cell Tumour of the Larynx
title_full Granular Cell Tumour of the Larynx
title_fullStr Granular Cell Tumour of the Larynx
title_full_unstemmed Granular Cell Tumour of the Larynx
title_short Granular Cell Tumour of the Larynx
title_sort granular cell tumour of the larynx
topic Sine qua non Clinicopathologic Correlation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082060/
https://www.ncbi.nlm.nih.gov/pubmed/27325237
http://dx.doi.org/10.1007/s12105-016-0736-3
work_keys_str_mv AT sproatrhona granularcelltumourofthelarynx
AT wonggentle granularcelltumourofthelarynx
AT rubinjohn granularcelltumourofthelarynx