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Granular Cell Tumour of the Larynx
A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, po...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082060/ https://www.ncbi.nlm.nih.gov/pubmed/27325237 http://dx.doi.org/10.1007/s12105-016-0736-3 |
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author | Sproat, Rhona Wong, Gentle Rubin, John |
author_facet | Sproat, Rhona Wong, Gentle Rubin, John |
author_sort | Sproat, Rhona |
collection | PubMed |
description | A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, positive for S-100 staining. This confirmed a granular cell tumour. CO(2) laser was utilised to excise this benign tumour. Granular cell tumours of the head and neck are common, but are infrequently found in the larynx. This case report highlights the importance for the otolaryngologist to be aware of this differential diagnosis, particularly as histologically they may be confused with squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-5082060 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-50820602016-11-09 Granular Cell Tumour of the Larynx Sproat, Rhona Wong, Gentle Rubin, John Head Neck Pathol Sine qua non Clinicopathologic Correlation A 55-year-old lady with a 6 month history of hoarse voice presented to our ENT department. Endoscopic examination displayed a white left arytenoid lesion. Biopsy of this lesion displayed a nodule covered with non-keratinizing stratified squamous epithelium, with a central core of polygonal cells, positive for S-100 staining. This confirmed a granular cell tumour. CO(2) laser was utilised to excise this benign tumour. Granular cell tumours of the head and neck are common, but are infrequently found in the larynx. This case report highlights the importance for the otolaryngologist to be aware of this differential diagnosis, particularly as histologically they may be confused with squamous cell carcinoma. Springer US 2016-06-20 /pmc/articles/PMC5082060/ /pubmed/27325237 http://dx.doi.org/10.1007/s12105-016-0736-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Sine qua non Clinicopathologic Correlation Sproat, Rhona Wong, Gentle Rubin, John Granular Cell Tumour of the Larynx |
title | Granular Cell Tumour of the Larynx |
title_full | Granular Cell Tumour of the Larynx |
title_fullStr | Granular Cell Tumour of the Larynx |
title_full_unstemmed | Granular Cell Tumour of the Larynx |
title_short | Granular Cell Tumour of the Larynx |
title_sort | granular cell tumour of the larynx |
topic | Sine qua non Clinicopathologic Correlation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082060/ https://www.ncbi.nlm.nih.gov/pubmed/27325237 http://dx.doi.org/10.1007/s12105-016-0736-3 |
work_keys_str_mv | AT sproatrhona granularcelltumourofthelarynx AT wonggentle granularcelltumourofthelarynx AT rubinjohn granularcelltumourofthelarynx |