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Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease

A 51-year-old man was diagnosed with Behçet’s disease in 2001. The patient was resistant to all immunosuppressive therapies. After 6 months of infliximab therapy, he presented to our clinic with pain and blurred vision in his right eye. The visual acuity was 20/200 and the intraocular pressure was 3...

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Autores principales: Gür Güngör, Sirel, Asena, Leyla, Akman, Ahmet, Gökmen, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082256/
https://www.ncbi.nlm.nih.gov/pubmed/27800267
http://dx.doi.org/10.4274/tjo.59354
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author Gür Güngör, Sirel
Asena, Leyla
Akman, Ahmet
Gökmen, Onur
author_facet Gür Güngör, Sirel
Asena, Leyla
Akman, Ahmet
Gökmen, Onur
author_sort Gür Güngör, Sirel
collection PubMed
description A 51-year-old man was diagnosed with Behçet’s disease in 2001. The patient was resistant to all immunosuppressive therapies. After 6 months of infliximab therapy, he presented to our clinic with pain and blurred vision in his right eye. The visual acuity was 20/200 and the intraocular pressure was 35 mmHg in the right eye. Biomicroscopic examination revealed corneal dendritic ulcers and 2+ cells in the anterior chamber in the right eye. The herpetic keratouveitis attack was controlled with antiviral therapy but the patient needed another glaucoma surgery. Trabeculectomy with mitomycin C was performed about halfway through an eight-week interval between two doses of infliximab.
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spelling pubmed-50822562016-10-31 Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease Gür Güngör, Sirel Asena, Leyla Akman, Ahmet Gökmen, Onur Turk J Ophthalmol Case Report A 51-year-old man was diagnosed with Behçet’s disease in 2001. The patient was resistant to all immunosuppressive therapies. After 6 months of infliximab therapy, he presented to our clinic with pain and blurred vision in his right eye. The visual acuity was 20/200 and the intraocular pressure was 35 mmHg in the right eye. Biomicroscopic examination revealed corneal dendritic ulcers and 2+ cells in the anterior chamber in the right eye. The herpetic keratouveitis attack was controlled with antiviral therapy but the patient needed another glaucoma surgery. Trabeculectomy with mitomycin C was performed about halfway through an eight-week interval between two doses of infliximab. Galenos Publishing 2016-04 2016-04-05 /pmc/articles/PMC5082256/ /pubmed/27800267 http://dx.doi.org/10.4274/tjo.59354 Text en ©Turkish Journal of Ophthalmology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gür Güngör, Sirel
Asena, Leyla
Akman, Ahmet
Gökmen, Onur
Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title_full Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title_fullStr Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title_full_unstemmed Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title_short Herpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
title_sort herpetic keratouveitis and trabeculectomy failure during infliximab therapy in a patient with behçet’s disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082256/
https://www.ncbi.nlm.nih.gov/pubmed/27800267
http://dx.doi.org/10.4274/tjo.59354
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