Comet Lesions in Patients with Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d...

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Detalles Bibliográficos
Autores principales: Tatlıpınar, Sinan, Şahan, Berna, Altunsoy, Muhsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082266/
https://www.ncbi.nlm.nih.gov/pubmed/27800246
http://dx.doi.org/10.4274/tjo.84756
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author Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
author_facet Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
author_sort Tatlıpınar, Sinan
collection PubMed
description Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d’orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions.
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spelling pubmed-50822662016-10-31 Comet Lesions in Patients with Pseudoxanthoma Elasticum Tatlıpınar, Sinan Şahan, Berna Altunsoy, Muhsin Turk J Ophthalmol Case Report Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d’orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions. Galenos Publishing 2015-12 2015-12-05 /pmc/articles/PMC5082266/ /pubmed/27800246 http://dx.doi.org/10.4274/tjo.84756 Text en ©Turkish Journal of Ophthalmology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
Comet Lesions in Patients with Pseudoxanthoma Elasticum
title Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_full Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_fullStr Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_full_unstemmed Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_short Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_sort comet lesions in patients with pseudoxanthoma elasticum
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082266/
https://www.ncbi.nlm.nih.gov/pubmed/27800246
http://dx.doi.org/10.4274/tjo.84756
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AT sahanberna cometlesionsinpatientswithpseudoxanthomaelasticum
AT altunsoymuhsin cometlesionsinpatientswithpseudoxanthomaelasticum

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