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Neuroprotective Effect of the Marine-Derived Compound 11-Dehydrosinulariolide through DJ-1-Related Pathway in In Vitro and In Vivo Models of Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by tremor, rigidity, bradykinesia, and gait impairment. In a previous study, we found that the marine-derived compound 11-dehydrosinulariolide (11-de) upregulates the Akt/PI3K pathway to protect cells against 6-hydroxydopamine (6...
Autores principales: | Feng, Chien-Wei, Hung, Han-Chun, Huang, Shi-Ying, Chen, Chun-Hong, Chen, Yun-Ru, Chen, Chun-Yu, Yang, San-Nan, Wang, Hui-Min David, Sung, Ping-Jyun, Sheu, Jyh-Horng, Tsui, Kuan-Hao, Chen, Wu-Fu, Wen, Zhi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082335/ https://www.ncbi.nlm.nih.gov/pubmed/27763504 http://dx.doi.org/10.3390/md14100187 |
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