“Inverse signaling” of the transmembrane chemokine CXCL16 contributes to proliferative and anti-apoptotic effects in cultured human meningioma cells

BACKGROUND: Chemokines and their receptors play a decisive role in tumor progression and metastasis. We recently found a new signaling mechanism in malignant glioma cells mediated by transmembrane chemokines that we termed “inverse signaling”. According to this hypothesis, soluble (s)-CXCL16 binds t...

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Detalles Bibliográficos
Autores principales: Hattermann, Kirsten, Bartsch, Kareen, Gebhardt, Henrike H., Mehdorn, H. Maximilian, Synowitz, Michael, Schmitt, Anne Dorothée, Mentlein, Rolf, Held-Feindt, Janka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082356/
https://www.ncbi.nlm.nih.gov/pubmed/27784296
http://dx.doi.org/10.1186/s12964-016-0149-7

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