Chronic multiscale imaging of neuronal activity in the awake common marmoset

We report a methodology to chronically record in vivo brain activity in the awake common marmoset. Over a month, stable imaging revealed macroscopic sensory maps in the somatosensory cortex and their underlying cellular activity with a high signal-to-noise ratio in the awake but not anesthetized sta...

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Detalles Bibliográficos
Autores principales: Yamada, Yoshiyuki, Matsumoto, Yoshifumi, Okahara, Norio, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082371/
https://www.ncbi.nlm.nih.gov/pubmed/27786241
http://dx.doi.org/10.1038/srep35722
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author Yamada, Yoshiyuki
Matsumoto, Yoshifumi
Okahara, Norio
Mikoshiba, Katsuhiko
author_facet Yamada, Yoshiyuki
Matsumoto, Yoshifumi
Okahara, Norio
Mikoshiba, Katsuhiko
author_sort Yamada, Yoshiyuki
collection PubMed
description We report a methodology to chronically record in vivo brain activity in the awake common marmoset. Over a month, stable imaging revealed macroscopic sensory maps in the somatosensory cortex and their underlying cellular activity with a high signal-to-noise ratio in the awake but not anesthetized state. This methodology is applicable to other brain regions, and will be useful for studying cortical activity and plasticity in marmosets during learning, development, and in neurological disorders.
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spelling pubmed-50823712016-10-31 Chronic multiscale imaging of neuronal activity in the awake common marmoset Yamada, Yoshiyuki Matsumoto, Yoshifumi Okahara, Norio Mikoshiba, Katsuhiko Sci Rep Article We report a methodology to chronically record in vivo brain activity in the awake common marmoset. Over a month, stable imaging revealed macroscopic sensory maps in the somatosensory cortex and their underlying cellular activity with a high signal-to-noise ratio in the awake but not anesthetized state. This methodology is applicable to other brain regions, and will be useful for studying cortical activity and plasticity in marmosets during learning, development, and in neurological disorders. Nature Publishing Group 2016-10-27 /pmc/articles/PMC5082371/ /pubmed/27786241 http://dx.doi.org/10.1038/srep35722 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Yamada, Yoshiyuki
Matsumoto, Yoshifumi
Okahara, Norio
Mikoshiba, Katsuhiko
Chronic multiscale imaging of neuronal activity in the awake common marmoset
title Chronic multiscale imaging of neuronal activity in the awake common marmoset
title_full Chronic multiscale imaging of neuronal activity in the awake common marmoset
title_fullStr Chronic multiscale imaging of neuronal activity in the awake common marmoset
title_full_unstemmed Chronic multiscale imaging of neuronal activity in the awake common marmoset
title_short Chronic multiscale imaging of neuronal activity in the awake common marmoset
title_sort chronic multiscale imaging of neuronal activity in the awake common marmoset
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082371/
https://www.ncbi.nlm.nih.gov/pubmed/27786241
http://dx.doi.org/10.1038/srep35722
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