HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway

Hepatitis C virus (HCV) establishes persistent infection in most infected patients, and eventually causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma in some patients. Monocytes and macrophages provide the first line of defense against pathogens, but their roles in HCV infection remai...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Wang, Yang, Zhai, Naicui, Song, Hongxiao, Li, Haijun, Yang, Yang, Li, Tianyang, Guo, Xiaolin, Chi, Baorong, Niu, Junqi, Crispe, Ian Nicholas, Su, Lishan, Tu, Zhengkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082373/
https://www.ncbi.nlm.nih.gov/pubmed/27786268
http://dx.doi.org/10.1038/srep36160

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