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Enantioconvergent catalysis

An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are...

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Detalles Bibliográficos
Autores principales: Mohr, Justin T, Moore, Jared T, Stoltz, Brian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082454/
https://www.ncbi.nlm.nih.gov/pubmed/27829909
http://dx.doi.org/10.3762/bjoc.12.192
Descripción
Sumario:An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods.