Potent triazine-based dehydrocondensing reagents substituted by an amido group

This study describes the synthesis of triazine-based dehydrocondensing reagents substituted by amido substituents and demonstrates their efficiency for dehydrocondensing reactions in MeOH and THF. N-Phenylbenzamido-substituted chlorotriazine is readily converted to a stable, non-hygroscopic triaziny...

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Autores principales: Kunishima, Munetaka, Kato, Daiki, Kimura, Nobu, Kitamura, Masanori, Yamada, Kohei, Hioki, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082469/
https://www.ncbi.nlm.nih.gov/pubmed/27829896
http://dx.doi.org/10.3762/bjoc.12.179
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author Kunishima, Munetaka
Kato, Daiki
Kimura, Nobu
Kitamura, Masanori
Yamada, Kohei
Hioki, Kazuhito
author_facet Kunishima, Munetaka
Kato, Daiki
Kimura, Nobu
Kitamura, Masanori
Yamada, Kohei
Hioki, Kazuhito
author_sort Kunishima, Munetaka
collection PubMed
description This study describes the synthesis of triazine-based dehydrocondensing reagents substituted by amido substituents and demonstrates their efficiency for dehydrocondensing reactions in MeOH and THF. N-Phenylbenzamido-substituted chlorotriazine is readily converted to a stable, non-hygroscopic triazinylammonium-based dehydrocondensing reagent that is superior to 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) in terms of its reactivity in dehydrocondensing reactions.
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spelling pubmed-50824692016-11-09 Potent triazine-based dehydrocondensing reagents substituted by an amido group Kunishima, Munetaka Kato, Daiki Kimura, Nobu Kitamura, Masanori Yamada, Kohei Hioki, Kazuhito Beilstein J Org Chem Full Research Paper This study describes the synthesis of triazine-based dehydrocondensing reagents substituted by amido substituents and demonstrates their efficiency for dehydrocondensing reactions in MeOH and THF. N-Phenylbenzamido-substituted chlorotriazine is readily converted to a stable, non-hygroscopic triazinylammonium-based dehydrocondensing reagent that is superior to 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) in terms of its reactivity in dehydrocondensing reactions. Beilstein-Institut 2016-08-24 /pmc/articles/PMC5082469/ /pubmed/27829896 http://dx.doi.org/10.3762/bjoc.12.179 Text en Copyright © 2016, Kunishima et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Kunishima, Munetaka
Kato, Daiki
Kimura, Nobu
Kitamura, Masanori
Yamada, Kohei
Hioki, Kazuhito
Potent triazine-based dehydrocondensing reagents substituted by an amido group
title Potent triazine-based dehydrocondensing reagents substituted by an amido group
title_full Potent triazine-based dehydrocondensing reagents substituted by an amido group
title_fullStr Potent triazine-based dehydrocondensing reagents substituted by an amido group
title_full_unstemmed Potent triazine-based dehydrocondensing reagents substituted by an amido group
title_short Potent triazine-based dehydrocondensing reagents substituted by an amido group
title_sort potent triazine-based dehydrocondensing reagents substituted by an amido group
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082469/
https://www.ncbi.nlm.nih.gov/pubmed/27829896
http://dx.doi.org/10.3762/bjoc.12.179
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