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Evidence for an iterative module in chain elongation on the azalomycin polyketide synthase
The assembly-line synthases that produce bacterial polyketide natural products follow a modular paradigm in which each round of chain extension is catalysed by a different set or module of enzymes. Examples of deviation from this paradigm, in which a module catalyses either multiple extensions or no...
Autores principales: | Hong, Hui, Sun, Yuhui, Zhou, Yongjun, Stephens, Emily, Samborskyy, Markiyan, Leadlay, Peter F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082578/ https://www.ncbi.nlm.nih.gov/pubmed/27829923 http://dx.doi.org/10.3762/bjoc.12.206 |
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