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Auditory perception in the aging brain: the role of inhibition and facilitation in early processing

Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the...

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Detalles Bibliográficos
Autores principales: Stothart, George, Kazanina, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082767/
https://www.ncbi.nlm.nih.gov/pubmed/27522518
http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022
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author Stothart, George
Kazanina, Nina
author_facet Stothart, George
Kazanina, Nina
author_sort Stothart, George
collection PubMed
description Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the role of cortical inhibition on auditory and audiovisual processing in younger and older adults. Across puretone, auditory and audiovisual speech paradigms older adults showed a consistent pattern of inhibitory deficits, manifested as increased P50 and/or N1 amplitudes and an absent or significantly reduced N2. Older adults were still able to use congruent visual articulatory information to aid auditory processing but appeared to require greater neural effort to resolve conflicts generated by incongruent visual information. In combination, the results provide support for the Inhibitory Deficit Hypothesis of aging. They extend previous findings into the audiovisual domain and highlight older adults' ability to benefit from congruent visual information during speech processing.
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spelling pubmed-50827672016-11-01 Auditory perception in the aging brain: the role of inhibition and facilitation in early processing Stothart, George Kazanina, Nina Neurobiol Aging Regular Article Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the role of cortical inhibition on auditory and audiovisual processing in younger and older adults. Across puretone, auditory and audiovisual speech paradigms older adults showed a consistent pattern of inhibitory deficits, manifested as increased P50 and/or N1 amplitudes and an absent or significantly reduced N2. Older adults were still able to use congruent visual articulatory information to aid auditory processing but appeared to require greater neural effort to resolve conflicts generated by incongruent visual information. In combination, the results provide support for the Inhibitory Deficit Hypothesis of aging. They extend previous findings into the audiovisual domain and highlight older adults' ability to benefit from congruent visual information during speech processing. Elsevier 2016-11 /pmc/articles/PMC5082767/ /pubmed/27522518 http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Regular Article
Stothart, George
Kazanina, Nina
Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title_full Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title_fullStr Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title_full_unstemmed Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title_short Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
title_sort auditory perception in the aging brain: the role of inhibition and facilitation in early processing
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082767/
https://www.ncbi.nlm.nih.gov/pubmed/27522518
http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022
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