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Auditory perception in the aging brain: the role of inhibition and facilitation in early processing
Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082767/ https://www.ncbi.nlm.nih.gov/pubmed/27522518 http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022 |
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author | Stothart, George Kazanina, Nina |
author_facet | Stothart, George Kazanina, Nina |
author_sort | Stothart, George |
collection | PubMed |
description | Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the role of cortical inhibition on auditory and audiovisual processing in younger and older adults. Across puretone, auditory and audiovisual speech paradigms older adults showed a consistent pattern of inhibitory deficits, manifested as increased P50 and/or N1 amplitudes and an absent or significantly reduced N2. Older adults were still able to use congruent visual articulatory information to aid auditory processing but appeared to require greater neural effort to resolve conflicts generated by incongruent visual information. In combination, the results provide support for the Inhibitory Deficit Hypothesis of aging. They extend previous findings into the audiovisual domain and highlight older adults' ability to benefit from congruent visual information during speech processing. |
format | Online Article Text |
id | pubmed-5082767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-50827672016-11-01 Auditory perception in the aging brain: the role of inhibition and facilitation in early processing Stothart, George Kazanina, Nina Neurobiol Aging Regular Article Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the role of cortical inhibition on auditory and audiovisual processing in younger and older adults. Across puretone, auditory and audiovisual speech paradigms older adults showed a consistent pattern of inhibitory deficits, manifested as increased P50 and/or N1 amplitudes and an absent or significantly reduced N2. Older adults were still able to use congruent visual articulatory information to aid auditory processing but appeared to require greater neural effort to resolve conflicts generated by incongruent visual information. In combination, the results provide support for the Inhibitory Deficit Hypothesis of aging. They extend previous findings into the audiovisual domain and highlight older adults' ability to benefit from congruent visual information during speech processing. Elsevier 2016-11 /pmc/articles/PMC5082767/ /pubmed/27522518 http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Regular Article Stothart, George Kazanina, Nina Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title | Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title_full | Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title_fullStr | Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title_full_unstemmed | Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title_short | Auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
title_sort | auditory perception in the aging brain: the role of inhibition and facilitation in early processing |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082767/ https://www.ncbi.nlm.nih.gov/pubmed/27522518 http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.022 |
work_keys_str_mv | AT stothartgeorge auditoryperceptionintheagingbraintheroleofinhibitionandfacilitationinearlyprocessing AT kazaninanina auditoryperceptionintheagingbraintheroleofinhibitionandfacilitationinearlyprocessing |