Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A

Various neurodegenerative disorders are associated with increased brain iron content. Iron is known to cause oxidative stress, which concomitantly promotes cell death. Whereas endolysosomes are known to serve as intracellular iron storage organelles, the consequences of increased iron on endolysosom...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández, Belén, Fdez, Elena, Gómez-Suaga, Patricia, Gil, Fernando, Molina-Villalba, Isabel, Ferrer, Isidro, Patel, Sandip, Churchill, Grant C., Hilfiker, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082776/
https://www.ncbi.nlm.nih.gov/pubmed/27383256
http://dx.doi.org/10.1080/15548627.2016.1190072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082776/
https://www.ncbi.nlm.nih.gov/pubmed/27383256
http://dx.doi.org/10.1080/15548627.2016.1190072

Ejemplares similares