Elevation of Alanine Aminotransferase Activity Occurs after Activation of the Cell-Death Signaling Initiated by Pattern-Recognition Receptors ‎but before Activation of Cytolytic Effectors in NK or CD8+ T Cells in the Liver During Acute HCV Infection

Pattern-recognition receptors (PRRs) promote host defenses against HCV infection by binding to their corresponding adapter molecules leading to the initiation of innate immune responses including cell death. We investigated the expression of PRR genes, biomarkers of liver cell-death, and T cell and...

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Detalles Bibliográficos
Autores principales: Choi, Youkyung H., Jin, Nancy, Kelly, Fiona, Sakthivel, SenthilKumar K., Yu, Tianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082795/
https://www.ncbi.nlm.nih.gov/pubmed/27788241
http://dx.doi.org/10.1371/journal.pone.0165533

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