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Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins
Anti-citrullinated protein antibodies (ACPA) have become an integral part of the clinical definition of rheumatoid arthritis, and are hypothesized to be important in the immunopathogenesis of this autoimmune disease. Several citrullinated proteins have been demonstrated to serve as candidate autoant...
Autores principales: | Meng, Xiaobo, Ezzati, Peyman, Smolik, Irene, Bernstein, Charles N., Hitchon, Carol Ann, El-Gabalawy, Hani S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082836/ https://www.ncbi.nlm.nih.gov/pubmed/27788229 http://dx.doi.org/10.1371/journal.pone.0165501 |
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