Cargando…

Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERα in Breast Cancer Cells

Endocrine therapy is the first-line targeted adjuvant therapy for hormone-sensitive breast cancer. In view of the potential anticancer property of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) together with chemotherapy in estrogen receptor alpha (ERα) positive mammary tumors, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	González-Bengtsson, Amanda, Asadi, Abolfazl, Gao, Hui, Dahlman-Wright, Karin, Jacobsson, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082882/ https://www.ncbi.nlm.nih.gov/pubmed/27788154 http://dx.doi.org/10.1371/journal.pone.0164241

Ejemplares similares

Polyunsaturated fatty acid elongation and desaturation in activated human T-cells: ELOVL5 is the key elongase
por: Robichaud, Philippe-Pierre, et al.
Publicado: (2018)

Remodeling of Retinal Fatty Acids in an Animal Model of Diabetes: A Decrease in Long-Chain Polyunsaturated Fatty Acids Is Associated With a Decrease in Fatty Acid Elongases Elovl2 and Elovl4
por: Tikhonenko, Maria, et al.
Publicado: (2010)

Glioblastoma Multiforme Tumors in Women Have a Lower Expression of Fatty Acid Elongases ELOVL2, ELOVL5, ELOVL6, and ELOVL7 than in Men
por: Korbecki, Jan, et al.
Publicado: (2022)

Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity
por: Logan, Sreemathi, et al.
Publicado: (2014)

The fatty acid elongase Elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation
por: Kiyoki, Yusuke, et al.
Publicado: (2023)

Dominant Elongase Activity of Elovl5a but Higher Expression of Elovl5b in Common Carp (Cyprinus carpio)
por: Zhao, Ran, et al.
Publicado: (2022)

Synergistic Effects of DHA and Sucrose on Body Weight Gain in PUFA-Deficient Elovl2 -/- Mice
por: Pauter, Anna M., et al.
Publicado: (2019)

P428: THE FATTY ACID ELONGASE ELOVL6 IS CRUCIAL FOR HEMATOPOIETIC STEM CELL ENGRAFTMENT AND LEUKEMIA PROPAGATION
por: Kiyoki, Yusuke, et al.
Publicado: (2023)

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea)
por: Li, Songlin, et al.
Publicado: (2017)

An evolutionary perspective on Elovl5 fatty acid elongase: comparison of Northern pike and duplicated paralogs from Atlantic salmon
por: Carmona-Antoñanzas, Greta, et al.
Publicado: (2013)

Reduced chain length in myelin sphingolipids and poorer motor coordination in mice deficient in the fatty acid elongase Elovl1
por: Isokawa, Masashi, et al.
Publicado: (2019)

TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
por: Xue, Jing, et al.
Publicado: (2021)

Elongase Reactions as Control Points in Long-Chain Polyunsaturated Fatty Acid Synthesis
por: Gregory, Melissa K., et al.
Publicado: (2011)

Heterologous expression of porcine elongase 6 (ELOVL6) gene in a human cell line
por: Gupta, Saurabh, et al.
Publicado: (2017)

Gene Expression of Desaturase (FADS1 and FADS2) and Elongase (ELOVL5) Enzymes in Peripheral Blood: Association with Polyunsaturated Fatty Acid Levels and Atopic Eczema in 4-Year-Old Children
por: Chisaguano, Aida Maribel, et al.
Publicado: (2013)

Two Modes of Regulation of the Fatty Acid Elongase ELOVL6 by the 3-Ketoacyl-CoA Reductase KAR in the Fatty Acid Elongation Cycle
por: Naganuma, Tatsuro, et al.
Publicado: (2014)

The Transcriptional Factor PPARαb Positively Regulates Elovl5 Elongase in Golden Pompano Trachinotus ovatus (Linnaeus 1758)
por: Zhu, Ke-Cheng, et al.
Publicado: (2018)

Fatty Acid Elongase 7 (ELOVL7) Plays a Role in the Synthesis of Long-Chain Unsaturated Fatty Acids in Goat Mammary Epithelial Cells
por: Shi, Hengbo, et al.
Publicado: (2019)

Elongation of very Long-Chain (>C(24)) Fatty Acids in Clarias gariepinus: Cloning, Functional Characterization and Tissue Expression of elovl4 Elongases
por: Oboh, Angela, et al.
Publicado: (2017)

Estrogen Promotes Hepatic Synthesis of Long-Chain Polyunsaturated Fatty Acids by Regulating ELOVL5 at Post-Transcriptional Level in Laying Hens
por: Zhang, Meng, et al.
Publicado: (2017)

Elovl2 ablation demonstrates that systemic DHA is endogenously produced and is essential for lipid homeostasis in mice
por: Pauter, Anna M., et al.
Publicado: (2014)

rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression
por: Pan, Gang, et al.
Publicado: (2020)

Molecular Cloning, Functional Characterization and Nutritional Regulation of the Putative Elongase Elovl5 in the Orange-Spotted Grouper (Epinephelus coioides)
por: Li, Songlin, et al.
Publicado: (2016)

Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Marine Gammarids: Molecular Cloning and Functional Characterisation of Three Fatty Acyl Elongases
por: Ribes-Navarro, Alberto, et al.
Publicado: (2021)

Effects of FADS and ELOVL polymorphisms on indexes of desaturase and elongase activities: results from a pre-post fish oil supplementation
por: Cormier, Hubert, et al.
Publicado: (2014)

Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria
por: Gómez Rodríguez, Alexia, et al.
Publicado: (2022)

Dual Fatty Acid Elongase Complex Interactions in Arabidopsis
por: Morineau, Céline, et al.
Publicado: (2016)

Tackling functional redundancy of Arabidopsis fatty acid elongase complexes
por: Batsale, Marguerite, et al.
Publicado: (2023)

ONION2 Fatty Acid Elongase is Required for Shoot Development in Rice
por: Tsuda, Katsutoshi, et al.
Publicado: (2013)

Co-expressing Eranthis hyemalis lysophosphatidic acid acyltransferase 2 and elongase improves two very long chain polyunsaturated fatty acid production in Brassica carinata
por: Meesapyodsuk, Dauenpen, et al.
Publicado: (2021)

Baldspot/ELOVL6 is a conserved modifier of disease and the ER stress response
por: Palu, Rebecca A. S., et al.
Publicado: (2018)

Combinatorial Effects of Fatty Acid Elongase Enzymes on Nervonic Acid Production in Camelina sativa
por: Huai, Dongxin, et al.
Publicado: (2015)

Fatty Acid Elongase 7 Catalyzes the Lipidome Remodeling Essential for Human Cytomegalovirus Replication
por: Purdy, John G., et al.
Publicado: (2015)

The fatty acid elongase Bond is essential for Drosophila sex pheromone synthesis and male fertility
por: Ng, Wan Chin, et al.
Publicado: (2015)

A single-cell platform for reconstituting and characterizing fatty acid elongase component enzymes
por: Campbell, Alexis A., et al.
Publicado: (2019)

Evolution of a fatty acyl–CoA elongase underlies desert adaptation in Drosophila
por: Wang, Zinan, et al.
Publicado: (2023)

Estrogen receptor β: an overview and update
por: Zhao, Chunyan, et al.
Publicado: (2008)

Single Nucleotide Polymorphisms in the FADS Gene Cluster but not the ELOVL2 Gene are Associated with Serum Polyunsaturated Fatty Acid Composition and Development of Allergy (in a Swedish Birth Cohort)
por: Barman, Malin, et al.
Publicado: (2015)

Association Analysis between Genetic Variants of elovl5a and elovl5b and Poly-Unsaturated Fatty Acids in Common Carp (Cyprinus carpio)
por: Zhang, Yan, et al.
Publicado: (2022)

Polymorphisms of Fatty Acid Elongase 2 Gene Afftects Risk of Pulmonary Tuberculosis in China Han Population
por: Mu, Min, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s2s5fs7mjhhne4jo9u183acpe3