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Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets

Pancreatic islets manage elevations in blood glucose level by secreting insulin into the bloodstream in a pulsatile manner. Pulsatile insulin secretion is governed by islet oscillations such as bursting electrical activity and periodic Ca(2+) entry in β-cells. In this report, we demonstrate that alt...

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Detalles Bibliográficos
Autores principales: McKenna, Joseph P., Dhumpa, Raghuram, Mukhitov, Nikita, Roper, Michael G., Bertram, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082885/
https://www.ncbi.nlm.nih.gov/pubmed/27788129
http://dx.doi.org/10.1371/journal.pcbi.1005143