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Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets
Pancreatic islets manage elevations in blood glucose level by secreting insulin into the bloodstream in a pulsatile manner. Pulsatile insulin secretion is governed by islet oscillations such as bursting electrical activity and periodic Ca(2+) entry in β-cells. In this report, we demonstrate that alt...
Autores principales: | McKenna, Joseph P., Dhumpa, Raghuram, Mukhitov, Nikita, Roper, Michael G., Bertram, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082885/ https://www.ncbi.nlm.nih.gov/pubmed/27788129 http://dx.doi.org/10.1371/journal.pcbi.1005143 |
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