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Perfluorocarbon-Loaded Lipid Nanocapsules to Assess the Dependence of U87-Human Glioblastoma Tumor pO(2) on In Vitro Expansion Conditions
Growing tumor cell lines, such as U87-MG glioma cells, under mild hypoxia (3% O(2)) leads to a ca. 40% reduction in growth rate once implanted in the brain of nude mice, as compared to normoxia (21% O(2)) grown cells, wherein the former over-express HIF-1 and VEGF-A. Despite developing differently,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082913/ https://www.ncbi.nlm.nih.gov/pubmed/27788227 http://dx.doi.org/10.1371/journal.pone.0165479 |