Cargando…

HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats

Older and even new antidepressants cause adverse effects, such as orthostatic hypotension, hyper- or hypoglycemia, liver injury or lipid disorders. In our previous experiments we showed significant antidepressant- and anxiolytic-like activities of dual 5-HT(1A) and 5-HT(7) antagonists with α(1)-adre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pytka, Karolina, Głuch-Lutwin, Monika, Knutelska, Joanna, Jakubczyk, Magdalena, Waszkielewicz, Anna, Kotańska, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082917/ https://www.ncbi.nlm.nih.gov/pubmed/27788267 http://dx.doi.org/10.1371/journal.pone.0165495

Ejemplares similares

Single Administration of HBK-15—a Triple 5-HT(1A), 5-HT(7), and 5-HT(3) Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone
por: Pytka, Karolina, et al.
Publicado: (2017)

HBK-14 and HBK-15 with antidepressant-like and/or memory-enhancing properties increase serotonin levels in the hippocampus after chronic treatment in mice
por: Pytka, Karolina, et al.
Publicado: (2016)

HBK-15, a Multimodal Compound, Showed an Anxiolytic-Like Effect in Rats
por: Lustyk, Klaudia, et al.
Publicado: (2022)

HBK-17, a 5-HT(1A) Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling
por: Pytka, Karolina, et al.
Publicado: (2018)

Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT(1A) and D(2) Receptors
por: Sałaciak, Kinga, et al.
Publicado: (2021)

HBK-10, A Compound with α(1)-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats
por: Lustyk, Klaudia, et al.
Publicado: (2022)

Biosynthesis of Pellucidin A in Peperomia pellucida (L.) HBK
por: de Moraes, Marcilio M., et al.
Publicado: (2021)

A Comparison of the Anorectic Effect and Safety of the Alpha(2)-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity
por: Dudek, Magdalena, et al.
Publicado: (2015)

Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT(1A) receptor partial agonists
por: Partyka, Anna, et al.
Publicado: (2020)

Principales usos del nanche (Byrsonima crassifolia (L.) H.B.K.) /
por: Martínez Moreno, Eusebio
Publicado: (2008)

Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation
por: Zajíčková, Markéta, et al.
Publicado: (2022)

Physicochemical characterization, fatty acid composition, and thermal analysis of Bertholletia excelsa HBK oil
por: Pena Muniz, Marcos Antônio, et al.
Publicado: (2015)

Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats
por: Florence, Ngueguim Tsofack, et al.
Publicado: (2017)

Selenium Accumulation, Speciation and Localization in Brazil Nuts (Bertholletia excelsa H.B.K.)
por: Lima, Leonardo W., et al.
Publicado: (2019)

Production of a Thermostable and Alkaline Chitinase by Bacillus thuringiensis subsp. kurstaki Strain HBK-51
por: Kuzu, Secil Berna, et al.
Publicado: (2012)

Development of a Nutraceutical Product Derived from By-Products of the Lipid Extraction of the Brazil Nut (Bertolletia excelsa H.B.K)
por: dos Santos, Orquidea Vasconcelos, et al.
Publicado: (2023)

In vitro effects of Blepharocalyx salicifolius (H.B.K.) O. Berg on the viability of Echinococcus ortleppi protoscoleces
por: Noal, Charlise Bolson, et al.
Publicado: (2017)

Dual Molecules Targeting 5-HT(6) and GABA-A Receptors as a New Approach to Combat Depression Associated with Neuroinflammation
por: Marcinkowska, Monika, et al.
Publicado: (2023)

Eugenia aurata and Eugenia punicifolia HBK inhibit inflammatory response by reducing neutrophil adhesion, degranulation and NET release
por: Costa, Mírian Feliciano, et al.
Publicado: (2016)

Phytochemical profiles of lemon verbena (Lippia citriodora H.B.K.) and its potential application to cookie enrichment
por: Hematian Sourki, Abdollah, et al.
Publicado: (2021)

Morphological and molecular characterization of an Elaeis oleifera (H.B.K) Cortes germplasm collection located in Ucayali, Peru
por: Camacho-Villalobos, Alina, et al.
Publicado: (2021)

Phytochemical Prospection and Modulation of Antibiotic Activity In Vitro by Lippia origanoides H.B.K. in Methicillin Resistant Staphylococcus aureus
por: Medeiros Barreto, Humberto, et al.
Publicado: (2014)

Non-Additive Effects on Decomposition from Mixing Litter of the Invasive Mikania micrantha H.B.K. with Native Plants
por: Chen, Bao-Ming, et al.
Publicado: (2013)

Genetic diversity of Elaeis oleifera (HBK) Cortes populations using cross species SSRs: implication’s for germplasm utilization and conservation
por: Ithnin, Maizura, et al.
Publicado: (2017)

Composition of Brazil Nut (Bertholletia excels HBK), Its Beverage and By-Products: A Healthy Food and Potential Source of Ingredients
por: Vasquez-Rojas, Wilson V., et al.
Publicado: (2021)

Identification and Quantification of Phenolic Compounds from Mexican Oregano (Lippia graveolens HBK) Hydroethanolic Extracts and Evaluation of Its Antioxidant Capacity
por: Cortés-Chitala, María del Carmen, et al.
Publicado: (2021)

Genome-wide identification and characterization of NBS-encoding genes in the sweet potato wild ancestor Ipomoea trifida (H.B.K.)
por: Si, Zengzhi, et al.
Publicado: (2022)

Effects of Regular Brazil Nut (Bertholletia excelsa H.B.K.) Consumption on Health: A Systematic Review of Clinical Trials
por: da Silva, Alessandra, et al.
Publicado: (2022)

The selective 5-HT(1A) receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress
por: Głuch-Lutwin, Monika, et al.
Publicado: (2021)

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT(1A) and 5-HT(7) Antagonists in Animal Models
por: Pytka, Karolina, et al.
Publicado: (2015)

Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor
por: Kotańska, Magdalena, et al.
Publicado: (2017)

MH-76, a Novel Non-Quinazoline α(1)-Adrenoceptor Antagonist, but Not Prazosin Reduces Inflammation and Improves Insulin Signaling in Adipose Tissue of Fructose-Fed Rats
por: Kubacka, Monika, et al.
Publicado: (2021)

El nance Byrsonima crassifolia (L.) H.B.K. como recurso natural antimicrobiano en enfermedades gastrointestinales y respiratorias
por: Moreno Gutiérrez, Maria Nereyda
Publicado: (2000)

Regeneration Capacity of Small Clonal Fragments of the Invasive Mikania micrantha H.B.K.: Effects of Burial Depth and Stolon Internode Length
por: Li, Xiaoxia, et al.
Publicado: (2013)

The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo
por: Huan, Yi, et al.
Publicado: (2017)

Novel Multimodal Salicylamide Derivative with Antidepressant-like, Anxiolytic-like, Antipsychotic-like, and Anti-Amnesic Activity in Mice
por: Żmudzka, Elżbieta, et al.
Publicado: (2023)

Caracterización molecular de los hongos formadores de ectomicorrizas asociados con abies religiosa (H.B.K.) schl. et Cham/
por: Ramos Fernández, Antero
Publicado: (2013)

Estudio etnobotánico sobre brahea dulcis (H.B.K.) Mart. (palma de sombrero) en la región de Jalcomulco, Veracruz /
por: Ramos Juárez, Yolanda
Publicado: (1988)

Microencapsulation, Chemical Characterization, and Antimicrobial Activity of Mexican (Lippia graveolens H.B.K.) and European (Origanum vulgare L.) Oregano Essential Oils
por: Hernández-Hernández, Elvia, et al.
Publicado: (2014)

Guanabenz—an old drug with a potential to decrease obesity
por: Kotańska, Magdalena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0rgvprf12t8f9i934h1h5q9206