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Brain Connectivity Changes in Autosomal Recessive Parkinson Disease: A Model for the Sporadic Form
Biallelic genetic mutations in the Park2 and PINK1 genes are frequent causes of autosomal recessive PD. Carriers of single heterozygous mutations may manifest subtle signs of disease, thus providing a unique model of preclinical PD. One emerging hypothesis suggests that non-motor symptom of PD, such...
Autores principales: | Makovac, Elena, Cercignani, Mara, Serra, Laura, Torso, Mario, Spanò, Barbara, Petrucci, Simona, Ricciardi, Lucia, Ginevrino, Monia, Caltagirone, Carlo, Bentivoglio, Anna Rita, Valente, Enza Maria, Bozzali, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082970/ https://www.ncbi.nlm.nih.gov/pubmed/27788143 http://dx.doi.org/10.1371/journal.pone.0163980 |
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