Cargando…

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

Pluripotent embryonic stem cells (ESCs) self-renew or differentiate into all tissues of the developing embryo and cell-specification factors are necessary to balance gene expression. Here we delineate the function of the PHD-finger protein 5a (Phf5a) in ESC self-renewal and ascribe its role in regul...

Descripción completa

Detalles Bibliográficos
Autores principales: Strikoudis, Alexandros, Lazaris, Charalampos, Trimarchi, Thomas, Neto, Antonio L. Galvao, Yang, Yan, Ntziachristos, Panagiotis, Rothbart, Scott, Buckley, Shannon, Dolgalev, Igor, Stadtfeld, Matthias, Strahl, Brian D., Dynlacht, Brian D., Tsirigos, Aristotelis, Aifantis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083132/
https://www.ncbi.nlm.nih.gov/pubmed/27749823
http://dx.doi.org/10.1038/ncb3424