Foxp2 Controls Synaptic Wiring of Corticostriatal Circuits and Vocal Communication by Opposing Mef2C

Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder (ASD), in which language function can be severely affected. We demonstrate that in the striatum, the gene, Foxp2, negatively interacts with the synapse suppressor, Mef2C. We present cau...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Chuan, Kuo, Hsiao-Ying, Bornschein, Ulrich, Takahashi, Hiroshi, Chen, Shih-Yun, Lu, Kuan-Ming, Yang, Hao-Yu, Chen, Gui-May, Lin, Jing-Ruei, Lee, Yi-Hsin, Chou, Yun-Chia, Cheng, Sin-Jhong, Chien, Cheng-Ting, Enard, Wolfgang, Hevers, Wulf, Pääbo, Svante, Graybiel, Ann M., Liu, Fu-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083203/
https://www.ncbi.nlm.nih.gov/pubmed/27595386
http://dx.doi.org/10.1038/nn.4380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083203/
https://www.ncbi.nlm.nih.gov/pubmed/27595386
http://dx.doi.org/10.1038/nn.4380

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