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Endoplasmic reticulum stress in chondrodysplasias caused by mutations in collagen types II and X
The endoplasmic reticulum is primarily recognized as the site of synthesis and folding of secreted, membrane-bound, and some organelle-targeted proteins. An imbalance between the load of unfolded proteins and the processing capacity in endoplasmic reticulum leads to the accumulation of unfolded or m...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083666/ https://www.ncbi.nlm.nih.gov/pubmed/27523816 http://dx.doi.org/10.1007/s12192-016-0719-z |