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A ‐1573T>C SNP within the human TRAIL promoter determines TRAIL expression and HCC tumor progression

The cytokine tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in liver cancer cells but not in normal liver cells. Therefore, TRAIL got credited to play a role in hepatocellular carcinoma (HCC) development and progression. Impaired expression of TRAIL in HCC ce...

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Detalles Bibliográficos
Autores principales: Piras‐Straub, Katja, Khairzada, Khaleda, Kocabayoglu, Peri, Paul, Andreas, Gerken, Guido, Herzer, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083748/
https://www.ncbi.nlm.nih.gov/pubmed/27580702
http://dx.doi.org/10.1002/cam4.854