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High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program
BACKGROUND: Atrial fibrillation, the world’s most common arrhythmia, is a leading risk factor for stroke, a disease striking nearly 1.6 million Indians annually. Early detection and management of atrial fibrillation is a promising opportunity to prevent stroke but widespread screening programs in li...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JMIR Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083844/ https://www.ncbi.nlm.nih.gov/pubmed/27737818 http://dx.doi.org/10.2196/publichealth.6517 |
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author | Soni, Apurv Earon, Allison Handorf, Anna Fahey, Nisha Talati, Kandarp Bostrom, John Chon, Ki Napolitano, Craig Chin, Michael Sullivan, John Raithatha, Shyamsundar Goldberg, Robert Nimbalkar, Somashekhar Allison, Jeroan Thanvi, Sunil McManus, David |
author_facet | Soni, Apurv Earon, Allison Handorf, Anna Fahey, Nisha Talati, Kandarp Bostrom, John Chon, Ki Napolitano, Craig Chin, Michael Sullivan, John Raithatha, Shyamsundar Goldberg, Robert Nimbalkar, Somashekhar Allison, Jeroan Thanvi, Sunil McManus, David |
author_sort | Soni, Apurv |
collection | PubMed |
description | BACKGROUND: Atrial fibrillation, the world’s most common arrhythmia, is a leading risk factor for stroke, a disease striking nearly 1.6 million Indians annually. Early detection and management of atrial fibrillation is a promising opportunity to prevent stroke but widespread screening programs in limited resource settings using conventional methods is difficult and costly. OBJECTIVE: The objective of this study is to screen people for atrial fibrillation in rural western India using a US Food and Drug Administration-approved single-lead electrocardiography device, Alivecor. METHODS: Residents from 6 villages in Anand District, Gujarat, India, comprised the base population. After obtaining informed consent, a team of trained research coordinators and community health workers enrolled a total of 354 participants aged 50 years and older and screened them at their residences using Alivecor for 2 minutes on 5 consecutive days over a period of 6 weeks beginning June, 2015. RESULTS: Almost two-thirds of study participants were 55 years or older, nearly half were female, one-third did not receive any formal education, and more than one-half were from households earning less than US $2 per day. Twelve participants screened positive for atrial fibrillation yielding a sample prevalence of 5.1% (95% CI 2.7-8.7). Only one participant had persistent atrial fibrillation throughout all of the screenings, and 9 screened positive only once. CONCLUSIONS: Our study suggests a prevalence of atrial fibrillation in this Indian region (5.1%) that is markedly higher than has been previously reported in India and similar to the prevalence estimates reported in studies of persons from North America and Europe. Historically low reported burden of atrial fibrillation among individuals from low and middle-income countries may be due to a lack of routine screening. Mobile technologies may help overcome resource limitations for atrial fibrillation screening in underserved and low-resource settings. |
format | Online Article Text |
id | pubmed-5083844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | JMIR Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-50838442016-11-07 High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program Soni, Apurv Earon, Allison Handorf, Anna Fahey, Nisha Talati, Kandarp Bostrom, John Chon, Ki Napolitano, Craig Chin, Michael Sullivan, John Raithatha, Shyamsundar Goldberg, Robert Nimbalkar, Somashekhar Allison, Jeroan Thanvi, Sunil McManus, David JMIR Public Health Surveill Short Paper BACKGROUND: Atrial fibrillation, the world’s most common arrhythmia, is a leading risk factor for stroke, a disease striking nearly 1.6 million Indians annually. Early detection and management of atrial fibrillation is a promising opportunity to prevent stroke but widespread screening programs in limited resource settings using conventional methods is difficult and costly. OBJECTIVE: The objective of this study is to screen people for atrial fibrillation in rural western India using a US Food and Drug Administration-approved single-lead electrocardiography device, Alivecor. METHODS: Residents from 6 villages in Anand District, Gujarat, India, comprised the base population. After obtaining informed consent, a team of trained research coordinators and community health workers enrolled a total of 354 participants aged 50 years and older and screened them at their residences using Alivecor for 2 minutes on 5 consecutive days over a period of 6 weeks beginning June, 2015. RESULTS: Almost two-thirds of study participants were 55 years or older, nearly half were female, one-third did not receive any formal education, and more than one-half were from households earning less than US $2 per day. Twelve participants screened positive for atrial fibrillation yielding a sample prevalence of 5.1% (95% CI 2.7-8.7). Only one participant had persistent atrial fibrillation throughout all of the screenings, and 9 screened positive only once. CONCLUSIONS: Our study suggests a prevalence of atrial fibrillation in this Indian region (5.1%) that is markedly higher than has been previously reported in India and similar to the prevalence estimates reported in studies of persons from North America and Europe. Historically low reported burden of atrial fibrillation among individuals from low and middle-income countries may be due to a lack of routine screening. Mobile technologies may help overcome resource limitations for atrial fibrillation screening in underserved and low-resource settings. JMIR Publications 2016-10-13 /pmc/articles/PMC5083844/ /pubmed/27737818 http://dx.doi.org/10.2196/publichealth.6517 Text en ©Apurv Soni, Allison Earon, Anna Handorf, Nisha Fahey, Kandarp Talati, John Bostrom, Ki Chon, Craig Napolitano, Michael Chin, John Sullivan, Shyamsundar Raithatha, Robert Goldberg, Somashekhar Nimbalkar, Jeroan Allison, Sunil Thanvi, David McManus. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 13.10.2016. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on http://publichealth.jmir.org, as well as this copyright and license information must be included. |
spellingShingle | Short Paper Soni, Apurv Earon, Allison Handorf, Anna Fahey, Nisha Talati, Kandarp Bostrom, John Chon, Ki Napolitano, Craig Chin, Michael Sullivan, John Raithatha, Shyamsundar Goldberg, Robert Nimbalkar, Somashekhar Allison, Jeroan Thanvi, Sunil McManus, David High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title | High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title_full | High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title_fullStr | High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title_full_unstemmed | High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title_short | High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program |
title_sort | high burden of unrecognized atrial fibrillation in rural india: an innovative community-based cross-sectional screening program |
topic | Short Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083844/ https://www.ncbi.nlm.nih.gov/pubmed/27737818 http://dx.doi.org/10.2196/publichealth.6517 |
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