Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies

Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or disc...

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Autores principales: Tomita, Takashi, Goto, Hidekazu, Sumiya, Kenji, Yoshida, Tadashi, Tanaka, Katsuya, Kohda, Yukinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083933/
https://www.ncbi.nlm.nih.gov/pubmed/27776394
http://dx.doi.org/10.9758/cpn.2016.14.4.391
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author Tomita, Takashi
Goto, Hidekazu
Sumiya, Kenji
Yoshida, Tadashi
Tanaka, Katsuya
Kohda, Yukinao
author_facet Tomita, Takashi
Goto, Hidekazu
Sumiya, Kenji
Yoshida, Tadashi
Tanaka, Katsuya
Kohda, Yukinao
author_sort Tomita, Takashi
collection PubMed
description Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or discontinuation of lithium carbonate, in whom adenine administration ameliorated the white blood cell and neutrophil counts. The progress of patients suggests that adenine is effective in cases of leukopenia and neutropenia associated with lithium carbonate discontinuation and an antipsychotic overdose.
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spelling pubmed-50839332016-11-01 Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies Tomita, Takashi Goto, Hidekazu Sumiya, Kenji Yoshida, Tadashi Tanaka, Katsuya Kohda, Yukinao Clin Psychopharmacol Neurosci Case Report Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or discontinuation of lithium carbonate, in whom adenine administration ameliorated the white blood cell and neutrophil counts. The progress of patients suggests that adenine is effective in cases of leukopenia and neutropenia associated with lithium carbonate discontinuation and an antipsychotic overdose. Korean College of Neuropsychopharmacology 2016-11 2016-11-30 /pmc/articles/PMC5083933/ /pubmed/27776394 http://dx.doi.org/10.9758/cpn.2016.14.4.391 Text en Copyright © 2016, Korean College of Neuropsychopharmacology This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tomita, Takashi
Goto, Hidekazu
Sumiya, Kenji
Yoshida, Tadashi
Tanaka, Katsuya
Kohda, Yukinao
Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title_full Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title_fullStr Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title_full_unstemmed Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title_short Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies
title_sort efficacy of adenine in the treatment of leukopenia and neutropenia associated with an overdose of antipsychotics or discontinuation of lithium carbonate administration: three case studies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083933/
https://www.ncbi.nlm.nih.gov/pubmed/27776394
http://dx.doi.org/10.9758/cpn.2016.14.4.391
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