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The Identification of Biochanin A as a Potent and Selective β-Site App-Cleaving Enzyme 1 (Bace1) Inhibitor

Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the enzyme involved in the abnormal production of the amyloidogenic peptide Aβ, one of the major causes of histological hallmarks of Alzheimer’s disease (AD). Thus, BACE1 represents a key target protein in the development of new potent...

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Detalles Bibliográficos
Autores principales:	Youn, Kumju, Park, Ji-Hyun, Lee, Jinhyuk, Jeong, Woo-Sik, Ho, Chi-Tang, Jun, Mira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084024/ https://www.ncbi.nlm.nih.gov/pubmed/27754406 http://dx.doi.org/10.3390/nu8100637

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