Cargando…
Late Stage Azidation of Complex Molecules
[Image: see text] Selective functionalization of complex scaffolds is a promising approach to alter the pharmacological profiles of natural products and their derivatives. We report the site-selective azidation of benzylic and aliphatic C–H bonds in complex molecules catalyzed by the combination of...
Autores principales: | Karimov, Rashad R., Sharma, Ankit, Hartwig, John F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084078/ https://www.ncbi.nlm.nih.gov/pubmed/27800554 http://dx.doi.org/10.1021/acscentsci.6b00214 |
Ejemplares similares
-
Metal-Catalyzed Azidation of Tertiary C–H Bonds Suitable for Late-Stage Functionalization
por: Sharma, Ankit, et al.
Publicado: (2015) -
Synthesis
and Late-Stage Functionalization of Complex
Molecules through C–H Fluorination and Nucleophilic Aromatic
Substitution
por: Fier, Patrick S., et al.
Publicado: (2014) -
Metal‐Catalysed Azidation of Organic Molecules
por: Goswami, Monalisa, et al.
Publicado: (2016) -
Discrete Cu(i) complexes for azide–alkyne annulations of small molecules inside mammalian cells
por: Miguel-Ávila, Joan, et al.
Publicado: (2018) -
Aryl Azides as Phosphine-Activated Switches for Small Molecule Function
por: Lukasak, Bradley, et al.
Publicado: (2019)