Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

Exosomes are nanovesicles released by virtually all cells, which act as intercellular messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes of cell uptake, and subcellular fate within recipient cells remain elusive. We quantitatively characterize exosome cell...

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Detalles Bibliográficos
Autores principales: Heusermann, Wolf, Hean, Justin, Trojer, Dominic, Steib, Emmanuelle, von Bueren, Stefan, Graff-Meyer, Alexandra, Genoud, Christel, Martin, Katrin, Pizzato, Nicolas, Voshol, Johannes, Morrissey, David V., Andaloussi, Samir E.L., Wood, Matthew J., Meisner-Kober, Nicole C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084269/
https://www.ncbi.nlm.nih.gov/pubmed/27114500
http://dx.doi.org/10.1083/jcb.201506084

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