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Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy

BACKGROUND: MEK1 (MAP2K1) and MEK2 (MAP2K2) are closely related dual-specificity protein kinases which function by phosphorylating both serine/threonine and tyrosine residues of their substrates ERK1 and ERK2, controlling fundamental cellular processes that include cell growth and proliferation. To...

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Detalles Bibliográficos
Autores principales:	Gomez-Millan, J., Pajares, B., Perez-Villa, L., Carnero, A., Alvarez, M., De Luque, V., Rivas, F., Trigo, J. M., Toledo, M. D., Alba, E., Medina, J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084350/ https://www.ncbi.nlm.nih.gov/pubmed/27793200 http://dx.doi.org/10.1186/s12885-016-2869-x

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