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In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes
BACKGROUND: The Neisseria meningitidis (Nm) chromosome shows a high abundance of simple sequence DNA repeats (SSRs) that undergo stochastic, reversible mutations at high frequency. This mechanism is reflected in an extensive phenotypic diversity that facilitates Nm adaptation to dynamic environmenta...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084427/ https://www.ncbi.nlm.nih.gov/pubmed/27793092 http://dx.doi.org/10.1186/s12864-016-3185-1 |