Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization

BACKGROUND: Transglutaminases (TGase), which are synthesized as a zymogen (pro-TGase) in Streptomyces sp., are important enzymes in the food industry. Because this pro-peptide is essential for the correct folding of Streptomyces TGase, TGase is usually expressed in an inactive pro-TGase form, which...

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Detalles Bibliográficos
Autores principales: Liu, Song, Wang, Miao, Du, Guocheng, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084433/
https://www.ncbi.nlm.nih.gov/pubmed/27793152
http://dx.doi.org/10.1186/s12896-016-0304-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084433/
https://www.ncbi.nlm.nih.gov/pubmed/27793152
http://dx.doi.org/10.1186/s12896-016-0304-7

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