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Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization
BACKGROUND: Transglutaminases (TGase), which are synthesized as a zymogen (pro-TGase) in Streptomyces sp., are important enzymes in the food industry. Because this pro-peptide is essential for the correct folding of Streptomyces TGase, TGase is usually expressed in an inactive pro-TGase form, which...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084433/ https://www.ncbi.nlm.nih.gov/pubmed/27793152 http://dx.doi.org/10.1186/s12896-016-0304-7 |