N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions

BACKGROUND: Mycobacterium tuberculosis infection is thought to induce oxidative stress. N-acetyl-cysteine (NAC) is widely used in patients with chronic pulmonary diseases including tuberculosis due to its mucolytic and anti-oxidant activities. Here, we tested whether NAC exerts a direct antibiotic a...

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Detalles Bibliográficos
Autores principales: Amaral, Eduardo P., Conceição, Elisabete L., Costa, Diego L., Rocha, Michael S., Marinho, Jamocyr M., Cordeiro-Santos, Marcelo, D’Império-Lima, Maria Regina, Barbosa, Theolis, Sher, Alan, Andrade, Bruno B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084440/
https://www.ncbi.nlm.nih.gov/pubmed/27793104
http://dx.doi.org/10.1186/s12866-016-0872-7

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