Mesenchymal stem cells improve mouse non-heart-beating liver graft survival by inhibiting Kupffer cell apoptosis via TLR4-ERK1/2-Fas/FasL-caspase3 pathway regulation

BACKGROUND: Liver transplantation is the optimal treatment option for end-stage liver disease, but organ shortages dramatically restrict its application. Donation after cardiac death (DCD) is an alternative approach that may expand the donor pool, but it faces challenges such as graft dysfunction, e...

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Detalles Bibliográficos
Autores principales: Tian, Yang, Wang, Jingcheng, Wang, Wei, Ding, Yuan, Sun, Zhongquan, Zhang, Qiyi, Wang, Yan, Xie, Haiyang, Yan, Sheng, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084468/
https://www.ncbi.nlm.nih.gov/pubmed/27788674
http://dx.doi.org/10.1186/s13287-016-0416-y

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