Not all elevated hormones are toxic: A case of thyroid hormone resistance

Resistance to thyroid hormone syndrome (RTH) is a rare disorder and is usually inherited as dominantly negative autosomal trait. RTH is caused by mutations in the thyroid hormone receptor beta. Patients with RTH usually do not have signs and symptoms of thyrotoxicosis, but the thyroid function test...

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Autores principales: Philip, Rajeev, Padikal, Mohan Krishnakumar, Alinausad, Altaf, Keshavan, Charamelsankaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084582/
https://www.ncbi.nlm.nih.gov/pubmed/27843862
http://dx.doi.org/10.4103/2249-4863.192339
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author Philip, Rajeev
Padikal, Mohan Krishnakumar
Alinausad, Altaf
Keshavan, Charamelsankaran
author_facet Philip, Rajeev
Padikal, Mohan Krishnakumar
Alinausad, Altaf
Keshavan, Charamelsankaran
author_sort Philip, Rajeev
collection PubMed
description Resistance to thyroid hormone syndrome (RTH) is a rare disorder and is usually inherited as dominantly negative autosomal trait. RTH is caused by mutations in the thyroid hormone receptor beta. Patients with RTH usually do not have signs and symptoms of thyrotoxicosis, but the thyroid function test shows an elevated T3 and T4, which get misinterpreted as hyperthyroidism, resulting in unnecessary treatment.
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spelling pubmed-50845822016-11-14 Not all elevated hormones are toxic: A case of thyroid hormone resistance Philip, Rajeev Padikal, Mohan Krishnakumar Alinausad, Altaf Keshavan, Charamelsankaran J Family Med Prim Care Case Report Resistance to thyroid hormone syndrome (RTH) is a rare disorder and is usually inherited as dominantly negative autosomal trait. RTH is caused by mutations in the thyroid hormone receptor beta. Patients with RTH usually do not have signs and symptoms of thyrotoxicosis, but the thyroid function test shows an elevated T3 and T4, which get misinterpreted as hyperthyroidism, resulting in unnecessary treatment. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5084582/ /pubmed/27843862 http://dx.doi.org/10.4103/2249-4863.192339 Text en Copyright: © Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Philip, Rajeev
Padikal, Mohan Krishnakumar
Alinausad, Altaf
Keshavan, Charamelsankaran
Not all elevated hormones are toxic: A case of thyroid hormone resistance
title Not all elevated hormones are toxic: A case of thyroid hormone resistance
title_full Not all elevated hormones are toxic: A case of thyroid hormone resistance
title_fullStr Not all elevated hormones are toxic: A case of thyroid hormone resistance
title_full_unstemmed Not all elevated hormones are toxic: A case of thyroid hormone resistance
title_short Not all elevated hormones are toxic: A case of thyroid hormone resistance
title_sort not all elevated hormones are toxic: a case of thyroid hormone resistance
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084582/
https://www.ncbi.nlm.nih.gov/pubmed/27843862
http://dx.doi.org/10.4103/2249-4863.192339
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AT alinausadaltaf notallelevatedhormonesaretoxicacaseofthyroidhormoneresistance
AT keshavancharamelsankaran notallelevatedhormonesaretoxicacaseofthyroidhormoneresistance

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