Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy

Our findings suggest that morphine dysregulates synaptic balance in the hippocampus, a key center for learning and memory, via a novel signaling pathway involving reactive oxygen species (ROS), endoplasmic reticulum (ER) stress, and autophagy. We demonstrate in this study that exposure of morphine t...

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Detalles Bibliográficos
Autores principales: Cai, Yu, Yang, Lu, Hu, Guoku, Chen, Xufeng, Niu, Fang, Yuan, Li, Liu, Han, Xiong, Huangui, Arikkath, Jyothi, Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084649/
https://www.ncbi.nlm.nih.gov/pubmed/27810915
http://dx.doi.org/10.1083/jcb.201605065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084649/
https://www.ncbi.nlm.nih.gov/pubmed/27810915
http://dx.doi.org/10.1083/jcb.201605065

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