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Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy
Our findings suggest that morphine dysregulates synaptic balance in the hippocampus, a key center for learning and memory, via a novel signaling pathway involving reactive oxygen species (ROS), endoplasmic reticulum (ER) stress, and autophagy. We demonstrate in this study that exposure of morphine t...
Autores principales: | Cai, Yu, Yang, Lu, Hu, Guoku, Chen, Xufeng, Niu, Fang, Yuan, Li, Liu, Han, Xiong, Huangui, Arikkath, Jyothi, Buch, Shilpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084649/ https://www.ncbi.nlm.nih.gov/pubmed/27810915 http://dx.doi.org/10.1083/jcb.201605065 |
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