Loss of YAP1 defines neuroendocrine differentiation of lung tumors

YAP1, the main Hippo pathway effector, is a potent oncogene and is overexpressed in non‐small‐cell lung cancer (NSCLC); however, the YAP1 expression pattern in small‐cell lung cancer (SCLC) has not yet been elucidated in detail. We report that the loss of YAP1 is a special feature of high‐grade neur...

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Detalles Bibliográficos
Autores principales: Ito, Takeshi, Matsubara, Daisuke, Tanaka, Ichidai, Makiya, Kanae, Tanei, Zen‐ichi, Kumagai, Yuki, Shiu, Shu‐Jen, Nakaoka, Hiroki J., Ishikawa, Shumpei, Isagawa, Takayuki, Morikawa, Teppei, Shinozaki‐Ushiku, Aya, Goto, Yasushi, Nakano, Tomoyuki, Tsuchiya, Takehiro, Tsubochi, Hiroyoshi, Komura, Daisuke, Aburatani, Hiroyuki, Dobashi, Yoh, Nakajima, Jun, Endo, Shunsuke, Fukayama, Masashi, Sekido, Yoshitaka, Niki, Toshiro, Murakami, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084673/
https://www.ncbi.nlm.nih.gov/pubmed/27418196
http://dx.doi.org/10.1111/cas.13013

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