Clofazimine Enteropathy: A Rare and Underrecognized Complication of Mycobacterial Therapy

Clofazimine-induced crystal-storing histiocytosis is a rare complication of treatment previously reported in dermatology literature as a complication of leprosy therapy. We report a case of disseminated Mycobacterium abscessus requiring treatment with high-dose oral clofazimine resulting in enteropa...

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Detalles Bibliográficos
Autores principales: Szeto, Winnie, Garcia-Buitrago, Monica T., Abbo, Lilian, Rosenblatt, Joseph D., Moshiree, Baharak, Morris, Michele I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084711/
https://www.ncbi.nlm.nih.gov/pubmed/27800519
http://dx.doi.org/10.1093/ofid/ofw004
Descripción
Sumario:Clofazimine-induced crystal-storing histiocytosis is a rare complication of treatment previously reported in dermatology literature as a complication of leprosy therapy. We report a case of disseminated Mycobacterium abscessus requiring treatment with high-dose oral clofazimine resulting in enteropathy in a patient who presented with abdominal pain, malnutrition, and melena.

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