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Crisaborole Topical Ointment, 2% in Patients Ages 2 to 17 Years with Atopic Dermatitis: A Phase 1b, Open‐Label, Maximal‐Use Systemic Exposure Study

BACKGROUND: Phosphodiesterase‐4 (PDE4) is a promising target in atopic dermatitis (AD) treatment. The pharmacokinetics (PK), safety, and efficacy of crisaborole topical ointment, 2% (formerly AN2728) (Anacor Pharmaceuticals, Palo Alto, CA), a boron‐based benzoxaborole PDE4 inhibitor, were evaluated...

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Detalles Bibliográficos
Autores principales:	Zane, Lee T., Kircik, Leon, Call, Robert, Tschen, Eduardo, Draelos, Zoe Diana, Chanda, Sanjay, Van Syoc, Merrie, Hebert, Adelaide A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084761/ https://www.ncbi.nlm.nih.gov/pubmed/27193740 http://dx.doi.org/10.1111/pde.12872

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