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Anatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?
RNA silencing is a eukaryote‐specific phenomenon in which microRNAs and small interfering RNAs degrade messenger RNAs containing a complementary sequence. To this end, these small RNAs need to be loaded onto an Argonaute protein (AGO protein) to form the effector complex referred to as RNA‐induced s...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Inc.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084781/ https://www.ncbi.nlm.nih.gov/pubmed/27184117 http://dx.doi.org/10.1002/wrna.1356 |