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Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection

Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has he...

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Detalles Bibliográficos
Autores principales: Chen, Shicheng, Soehnlen, Marty, Walker, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084858/
https://www.ncbi.nlm.nih.gov/pubmed/27789634
http://dx.doi.org/10.1128/genomeA.01137-16
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author Chen, Shicheng
Soehnlen, Marty
Walker, Edward D.
author_facet Chen, Shicheng
Soehnlen, Marty
Walker, Edward D.
author_sort Chen, Shicheng
collection PubMed
description Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has hemolysin genes and a set of genes involved in heme uptake and heme utilization, showing its potential to cause bloodstream infections. A clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (CRISPR/Cas) system was identified. Average nucleotide identity (ANI) analysis assigned the bacterium to the species E. meningoseptica (ANI, >95%). The annotated genome sequence provides the genetic basis for revealing its role as a pathogen in humans.
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spelling pubmed-50848582016-11-11 Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection Chen, Shicheng Soehnlen, Marty Walker, Edward D. Genome Announc Prokaryotes Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has hemolysin genes and a set of genes involved in heme uptake and heme utilization, showing its potential to cause bloodstream infections. A clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (CRISPR/Cas) system was identified. Average nucleotide identity (ANI) analysis assigned the bacterium to the species E. meningoseptica (ANI, >95%). The annotated genome sequence provides the genetic basis for revealing its role as a pathogen in humans. American Society for Microbiology 2016-10-27 /pmc/articles/PMC5084858/ /pubmed/27789634 http://dx.doi.org/10.1128/genomeA.01137-16 Text en Copyright © 2016 Chen et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Chen, Shicheng
Soehnlen, Marty
Walker, Edward D.
Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title_full Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title_fullStr Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title_full_unstemmed Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title_short Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
title_sort genome sequence of elizabethkingia meningoseptica em1, isolated from a patient with a bloodstream infection
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084858/
https://www.ncbi.nlm.nih.gov/pubmed/27789634
http://dx.doi.org/10.1128/genomeA.01137-16
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