Cargando…
Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection
Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has he...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084858/ https://www.ncbi.nlm.nih.gov/pubmed/27789634 http://dx.doi.org/10.1128/genomeA.01137-16 |
_version_ | 1782463468493864960 |
---|---|
author | Chen, Shicheng Soehnlen, Marty Walker, Edward D. |
author_facet | Chen, Shicheng Soehnlen, Marty Walker, Edward D. |
author_sort | Chen, Shicheng |
collection | PubMed |
description | Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has hemolysin genes and a set of genes involved in heme uptake and heme utilization, showing its potential to cause bloodstream infections. A clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (CRISPR/Cas) system was identified. Average nucleotide identity (ANI) analysis assigned the bacterium to the species E. meningoseptica (ANI, >95%). The annotated genome sequence provides the genetic basis for revealing its role as a pathogen in humans. |
format | Online Article Text |
id | pubmed-5084858 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-50848582016-11-11 Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection Chen, Shicheng Soehnlen, Marty Walker, Edward D. Genome Announc Prokaryotes Elizabethkingia meningoseptica EM1 was isolated from a whole-blood sample from a female patient. The draft genome sequence of Em1 contains 4,038,467 bp, with a G+C content of 36.37%. A preliminary genome analysis showed that Em1 contains genes conferring resistance to β-lactams. The bacterium has hemolysin genes and a set of genes involved in heme uptake and heme utilization, showing its potential to cause bloodstream infections. A clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (CRISPR/Cas) system was identified. Average nucleotide identity (ANI) analysis assigned the bacterium to the species E. meningoseptica (ANI, >95%). The annotated genome sequence provides the genetic basis for revealing its role as a pathogen in humans. American Society for Microbiology 2016-10-27 /pmc/articles/PMC5084858/ /pubmed/27789634 http://dx.doi.org/10.1128/genomeA.01137-16 Text en Copyright © 2016 Chen et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Prokaryotes Chen, Shicheng Soehnlen, Marty Walker, Edward D. Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title | Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title_full | Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title_fullStr | Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title_full_unstemmed | Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title_short | Genome Sequence of Elizabethkingia meningoseptica EM1, Isolated from a Patient with a Bloodstream Infection |
title_sort | genome sequence of elizabethkingia meningoseptica em1, isolated from a patient with a bloodstream infection |
topic | Prokaryotes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084858/ https://www.ncbi.nlm.nih.gov/pubmed/27789634 http://dx.doi.org/10.1128/genomeA.01137-16 |
work_keys_str_mv | AT chenshicheng genomesequenceofelizabethkingiameningosepticaem1isolatedfromapatientwithabloodstreaminfection AT soehnlenmarty genomesequenceofelizabethkingiameningosepticaem1isolatedfromapatientwithabloodstreaminfection AT walkeredwardd genomesequenceofelizabethkingiameningosepticaem1isolatedfromapatientwithabloodstreaminfection |